Healing, hormones & brain
KPV
Lys-Pro-Val
An anti-inflammatory tripeptide studied in cells and mice.
Peptide · 3 amino acids
Lab & animal studies only
What it is
A three-amino-acid peptide taken from the end of α-MSH, a natural hormone with anti-inflammatory effects.
How it's thought to work
It appears to dampen inflammatory signaling (NF-κB) inside cells.
What the evidence shows
It reduced inflammation in cell and mouse models of colitis and skin inflammation. No human trials have been published.
Regulatory status
Not approved for any use.
Safety notes
Human safety data are lacking.
Key sources
- Dalmasso G, et al. PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation. Gastroenterology. 2008. Find on PubMed
Educational summary only, not medical advice. Gtides does not sell or link to sellers of KPV or any other product. Products sold as “research peptides” are not approved medicines, and their contents, purity and sterility are not verified.