Healing, hormones & brain

Kisspeptin

Kisspeptin-10

The hormone that switches on the reproductive system, used in research studies.

Peptide · reproductive hormone
Small human studies

What it is

A hormone made in the hypothalamus. Kisspeptin-10 is its shortest active form.

How it's thought to work

It triggers release of GnRH, which drives LH, FSH and the sex hormones that control puberty and fertility.

What the evidence shows

It has been given to people in research settings, including IVF trials using it (as kisspeptin-54) to trigger egg maturation and studies of sexual and emotional brain responses.

Regulatory status

Research use only. Not approved as a medicine.

Safety notes

Generally well tolerated in short research studies. Repeated or continuous exposure can desensitise the reproductive hormone system.

Key sources

  • Abbara A, et al. Efficacy of kisspeptin-54 to trigger oocyte maturation in women at high risk of ovarian hyperstimulation syndrome. J Clin Invest. 2015. Find on PubMed

Educational summary only, not medical advice. Gtides does not sell or link to sellers of Kisspeptin or any other product. Products sold as “research peptides” are not approved medicines, and their contents, purity and sterility are not verified.

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