Metabolism & weight
5-Amino-1MQ
A small-molecule enzyme blocker, often sold alongside peptides, studied only in animals.
What it is
Despite being sold alongside peptides, 5-amino-1MQ is a small molecule, not a peptide. It blocks an enzyme called NNMT (nicotinamide N-methyltransferase).
How it's thought to work
NNMT is highly active in fat tissue. Blocking it is thought to shift fat cells toward burning more energy and storing less fat.
What the evidence shows
In mice with diet-induced obesity, it reduced body weight and fat mass. No human clinical trials have been published.
Regulatory status
Not approved for any use.
Safety notes
Its safety in humans is unknown.
Key sources
- Neelakantan H, et al. Selective and membrane-permeable small molecule inhibitors of NNMT reverse high fat diet-induced obesity in mice. Biochem Pharmacol. 2018. Find on PubMed
Educational summary only, not medical advice. Gtides does not sell or link to sellers of 5-Amino-1MQ or any other product. Products sold as “research peptides” are not approved medicines, and their contents, purity and sterility are not verified.